Acute Lymphocytic Leukemia - Objectives
1. Using the Case Study Workbook, discuss functions and properties of blood to include:
- a. three general functions
- b. components of blood including plasma and formed elements
- c. five primary types of WBCs and their function
- d. differentiate between granular and agranular WBCs
- e. describe the origin and development of blood cells
- f. define hemopoesis (hematopoiesis)
- g. define key cells involved in blood cell formation including pluipotent stem cells, myeloid and lymphoid stem cells, blasts.
- h. define cell types that come from the myeloid line and those that come from the lymphoid line.
- i. Describe pathological conditions in which each WBC type may be elevated or decreased (See table 19.2).
- j. Define the percentage of each type of WBC in the blood (See table 19.3).
2. Define the following terms: anemia, leukopenia, leukocytosis, lymphoblast, thrombocyte, blasts, blood-brain barrier, hypercellularity, meninges, pneumonia, pus, petechiae, remission, upper-lobe infiltrate, transfusion.
3. Discuss a CBC
- a. Define CBC, WBC, RBC, Hb, Hct, and platelets.
- b. List 5 pathological conditions that may cause an elevation in the WBC count.
4. Discuss the diagnostic testing used to diagnose leukemia to including throat culture, bone marrow aspirate, lumbar puncture, and chest x-ray.
- a. Define the principle of the test.
- b. Describe when the test is indicated.
- c. Describe how the test is performed.
- d. Summarize the diseases that can be diagnosed by the test.
5. Discuss a gram stain:
- a. Define the two groups of bacteria differentiated by a gram stain.
- b. Discuss why the gram stain is an important first step in the identification of a pathogen.
6. Discuss leukemia:
- a. List the 4 major types of leukemia.
- b. Define the predominant age group of each type of leukemia.
- c. Describe the difference between a lymphocytic and a myeloid leukemia.
- d. Describe the difference between an acute and chronic leukemia.
- e. Describe how an acute leukemia is treated differently than a chronic leukemia.
- f. List possible risk factors of leukemia.
- g. Describe the clinical symptoms of leukemia.
- h. Describe the procedures used to diagnose leukemia.
7. Review the following treatments for leukemia: chemotherapy, radiation, bone marrow transplant.
- a. Define the principle of the treatment.
- b. Describe how the treatment is given.
- c. Discuss the benefits and side affects of treatment.
8. Discuss the role of the following health care professionals in diagnosing and/or treating a patient with leukemia:
- a. physician to include the following physician specialties: pediatrician, oncologist, radiation oncologist, pathologist, and radiologist.
- b. medical laboratory technologist
- c. registered nurse
- d. radiology technician
- e. respiratory therapist