Acute Lymphocytic Leukemia - Objectives


1. Using the Case Study Workbook, discuss functions and properties of blood to include:

  • a. three general functions
  • b. components of blood including plasma and formed elements
  • c. five primary types of WBCs and their function
  • d. differentiate between granular and agranular WBCs
  • e. describe the origin and development of blood cells
  • f. define hemopoesis (hematopoiesis)
  • g. define key cells involved in blood cell formation including pluipotent stem cells, myeloid and lymphoid stem cells, blasts.
  • h. define cell types that come from the myeloid line and those that come from the lymphoid line.
  • i. Describe pathological conditions in which each WBC type may be elevated or decreased (See table 19.2).
  • j. Define the percentage of each type of WBC in the blood (See table 19.3).

 

2. Define the following terms: anemia, leukopenia, leukocytosis, lymphoblast, thrombocyte, blasts, blood-brain barrier, hypercellularity, meninges, pneumonia, pus, petechiae, remission, upper-lobe infiltrate, transfusion.

 

3. Discuss a CBC

  • a. Define CBC, WBC, RBC, Hb, Hct, and platelets.
  • b. List 5 pathological conditions that may cause an elevation in the WBC count.
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4. Discuss the diagnostic testing used to diagnose leukemia to including throat culture, bone marrow aspirate, lumbar puncture, and chest x-ray.

  • a. Define the principle of the test.
  • b. Describe when the test is indicated.
  • c. Describe how the test is performed.
  • d. Summarize the diseases that can be diagnosed by the test.
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5. Discuss a gram stain:

  • a. Define the two groups of bacteria differentiated by a gram stain.
  • b. Discuss why the gram stain is an important first step in the identification of a pathogen.
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6. Discuss leukemia:

  • a. List the 4 major types of leukemia.
  • b. Define the predominant age group of each type of leukemia.
  • c. Describe the difference between a lymphocytic and a myeloid leukemia.
  • d. Describe the difference between an acute and chronic leukemia.
  • e. Describe how an acute leukemia is treated differently than a chronic leukemia.
  • f. List possible risk factors of leukemia.
  • g. Describe the clinical symptoms of leukemia.
  • h. Describe the procedures used to diagnose leukemia.

 

7. Review the following treatments for leukemia: chemotherapy, radiation, bone marrow transplant.

  • a. Define the principle of the treatment.
  • b. Describe how the treatment is given.
  • c. Discuss the benefits and side affects of treatment.
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8. Discuss the role of the following health care professionals in diagnosing and/or treating a patient with leukemia:

  • a. physician to include the following physician specialties: pediatrician, oncologist, radiation oncologist, pathologist, and radiologist.
  • b. medical laboratory technologist
  • c. registered nurse
  • d. radiology technician
  • e. respiratory therapist